IMMUNOGENETICS OF TYPE I DIABETES MELLITUS

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Immunogenetics of type 1 diabetes mellitus Azza

Introduction Type 1 diabetes mellitus (T1D) is one of the most common autoimmune diseases with several million people already affected around the globe. It can occur at any age, but is most commonly diagnosed from infancy to the late thirties. It is characterized by an absolute loss of insulin secretion, and results from an autoimmune process that destroys insulinproducing ß cells within the pa...

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Immunogenetics of type 1 diabetes.

The T-cell mediated autoimmune process that destroys pancreatic beta cells in type 1 diabetes (T1D) is a complex phenotype influenced by multiple genetic and environmental factors. Human leukocyte antigen (HLA) accounts for about half of the genetic susceptibility, through a large variety of protective and predisposing haplotypes. Other important loci associated with T1D, with much smaller effe...

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Evaluation of Electrocardiographic Parameters in Diabetes Mellitus Type I in Children and Adolescent

  Background   Cardiovascular complications are continuing to be a major cause of morbidity and mortality in diabetes mellitus type I (DMTI). The study aimed to evaluate the rate of changes in ECG parameters in children with DMTI compared with healthy childr...

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The Prevalence of Limited Joint Mobility in Patients with Type I Diabetes Mellitus in Kerman

Background & Aims: Limited joint mobility (LJM) is a complication of diabetes mellitus, which usually begins from the small joints of hands and is associated with long-term complications of diabetes, such as retinopathy and nephropathy. The aim of this study was to find the prevalence of Limited Joint Mobility in patients with type 1 diabetes mellitus in Kerman in 2003. Methods: Sixty-six patie...

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PREVALENCE OF CELIAC DISEASE IN CHILDREN AND ADOLESCENTS WITH TYPE I DIABETES MELLITUS

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ژورنال

عنوان ژورنال: Pediatric Research

سال: 1993

ISSN: 0031-3998,1530-0447

DOI: 10.1203/00006450-199305001-00032